Case study

Cochrane Register of Studies Database (CRS-D)

Linking everything together - a database of all Cochrane studies and references


The Cochrane Register of Studies Database (CRS-D) is the culmination of 20 years of Cochrane research and is continually being added to as part of Cochrane’s mission to provide the best healthcare evidence-base in the world.

This data store links together data that were once fragmented. Diverse records are now in one place, links between studies and other data are now formalised, which means that everything known about a study can be retrieved with a simple query to the data store.

Source: Cochrane Collaboration

Overall objectives of CRS-D

To maximise the opportunities and capitalise on the work done by the whole Cochrane organisation, making the retrieval of records and links between data more accessible.

To provide enhanced support in the production and maintenance of quality Cochrane reviews, enhancing the content of all collected data regardless of its form and location.

To link everything together.

The role of Metaxis

To design, develop and build the entire database structure and the APIs providing access to links between all records, and to run and maintain the solution that sits at the heart of the Cochrane information ecosystem.

Metaxis developed sophisticated probabilistic matching techniques to underpin the intelligent design of CRS-D. This enables CRS-D to collate all the reviews that a study appears in, plus all other references to that study regardless of which review they appear in or where they are located across the ecosystem.

All records are linked together – references to studies, studies to reviews and to other parts of the ecosystem.

This creates an integrated and intuitive resource for authors and editorial teams which increases the efficiency of the production process and vastly improves access to study data. CRS-D is designed to manage the building blocks of reviews – collating all the records and making them available in one place reduces duplication of effort enormously.

The whole ethos of Cochrane is collaboration. The CRS-D, by formalising the links between records is enabling sharing across the whole ecosystem and potentially extending the reach, influence and use of Cochrane evidence globally.

Key features:

  • Bespoke design and development of database and APIs – a unifying solution
  • Sophisticated probabilistic matching – intelligent design to enhance data links
  • Fully integrated with the rest of the Cochrane information ecosystem

Key benefits:

  • Fast and improved access to data and production process
  • Duplication of effort in finding relevant data and information significantly reduced
  • Enriched content in one place
  • Extended use of Cochrane evidence

About Metaxis Ltd

Metaxis is a software development company based in the UK specialising in content management solutions and workflow control software. Our solutions support digital collaborative working environments where multiple users, regardless of their global location, can access and interact with high quality, relevant data and information in a meaningful and productive way.

Metaxis provides bespoke solutions rooted in best practice Agile methodology. Its software design principles – rapid behaviour-driven development, high performance, close client collaboration and ease of use – underpin the company’s business ethos.  Metaxis makes short work of Big Data.

Metaxis Ltd, Elmbank Court, Main Road, Curbridge, Witney OX29 7NT, UK  Tel: +44 (0)1993 771740